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Sanatan Upmanyu

About.

I’m a data-science executive with 18+ years spanning wet-lab biology, AI/ML engineering, HPC/cloud infrastructure, and leadership across pharma, biotech, and consumer health.

I architected the AlphaMeld™ platform — an end-to-end AI stack that accelerates target triage and indication selection for global drug-makers. My work covers clinical-trial design and enrollment prediction, digital-twin modelling, and large-scale knowledge-graph analytics.

I care about converting multimodal data into real business value, scaling cross-site teams, and forging the kind of partnerships that redefine R&D.

Sanatan Upmanyu

Career

  1. Dec 2024 – Present
    Apxora GmbHnow
    Co-Founder & AI/Data Science Head · Basel, Switzerland
    • Drives development and deployment of the ResearchNexus and Clinical Navigator platforms.
    • Leads strategic AI/ML initiatives for detecting early innovation signals for emerging targets, novel therapeutics, and healthcare solutions.
    • Supports the Asset Lifecycle Manager and Portfolio Management platforms.
  2. Sep 2024 – Present
    RenaissThera Pvt Ltdnow
    Scientific Advisory Board · Gurgaon, India
    • Advising on AI-driven strategies for early-stage drug discovery and translational research.
    • Shaping the future of health through regulatory-aware innovation in digital and data sciences.
  3. Dec 2020 – Present
    AlphaMeld GmbH (formerly InveniAI GmbH)now
    Head of Data Sciences – Site Head · Basel, Switzerland
    • Leads development and deployment of the AlphaMeld Platform.
    • Spearheads strategic AI/ML initiatives to enhance AlphaMeld/AlphaCompass capacity.
    • Advises pharma/biotech companies on leveraging data science methodologies.
    • Applied deep molecular biology expertise for MOA analyses and therapeutic target viability.
    • Manages a data science team of 5 members.
  4. Sep 2017 – Present
    ArtiXio Pvt Ltdnow
    Board of Director & Technical Advisor · Gurgaon, India
    • Conceptualized, built, and executed regulatory-compliant solutions across the drug development lifecycle.
    • Directed enterprise-level data science and AI product development using Agile methodologies.
    • Strategic consulting on technology adoption, regulatory intelligence, and compliance-driven digital transformation.
  5. Sep 2017 – Nov 2020
    InveniAI LLC
    Senior Director of Data Science · Hybrid Gurgaon IN / CT US
    • Conceptualized, built, and executed innovative solutions throughout the drug development lifecycle.
    • Managed enterprise-level data science products using Agile methodologies.
    • Established short- to long-term strategies for Data Science and AI teams.
  6. Apr 2014 – Aug 2017
    EZ BioXcel Pvt Ltd
    Director of Data Science · Hybrid Gurgaon IN / CT US
    • Directed drug repurposing and novel target hypothesis generation using big data and statistical techniques.
    • Managed and mentored a team of data scientists.
    • Collaborated with US-based pharma and biotech clients.
  7. Nov 2010 – Apr 2014
    EZ BioXcel Pvt Ltd
    Senior Analyst – Scientific Analytics · Hybrid Gurgaon IN / CT US
    • Directed project management and strategy consulting efforts.
    • Provided scientific support to business development.
    • Partnered with US-based clients on data-driven insights.
  8. Feb 2008 – Aug 2010
    NDDR – Ranbaxy
    Research Biologist / Fellowship · Gurgaon, India
    • Conducted siRNA targeted gene silencing for target-based drug discovery.
    • Cloning, expression, purification, and activity analysis of human kinases, cytochrome P450 proteins, GPCRs, and bacterial enzymes.
    • Managed experiments using mammalian, baculovirus, and Dictyostelium expression systems.

Education